Not truth for me. I played for a few hours and my eyes were no worse off than normal. They suggest taking a break every half-hour or so, which I often do anyway, but really it's no worse than playing PSP or DS for long stretches. The problem is that everyone's eyes are different and not everyone is going to be clever enough to know where to set the 3D sensitivity. Figure all of that out--which doesn't take long--and it's great... at least so far. I've only put a lot of time into a total of two games so far: Pilotwings Resort (obviously) and Super Street Fighter IV (which doesn't feel like it should really be possible or as excellent as it is on a Nintendo handheld).
"Too often we enjoy the comfort of opinion without the discomfort of thought." - John F. Kennedy on reality
"What if everything you see is more than what you see--the person next to you is a warrior and the space that appears empty is a secret door to another world? What if something appears that shouldn't? You either dismiss it, or you accept that there is much more to the world than you think. Perhaps it really is a doorway, and if you choose to go inside, you'll find many unexpected things." - Shigeru Miyamoto on secret doors to another world